ESBLs: A Clear and Present Danger?
نویسندگان
چکیده
Extended spectrum β-lactamases (ESBLs) are enzymes produced by a variety of Gram negative bacteria which confer an increased resistance to commonly used antibiotics. They are a worrying global public health issue as infections caused by such enzyme-producing organisms are associated with a higher morbidity and mortality and greater fiscal burden. Coupled with increasing prevalence rates worldwide and an ever diminishing supply in the antibiotic armamentarium, these enzymes represent a clear and present danger to public health. This article aims to give an overview of the current situation regarding ESBLs, with a focus on the epidemiology and management of such infections.
منابع مشابه
Molecular Epidemiology of ESBL Genes and Multi-Drug Resistance in Diarrheagenic Escherichia coli strains Isolated from Adults in Iran
Resistance to oxyimino cephalosporins antibiotics in Enterobacteriaceae is primarily done by the extended spectrum β-lactamases (ESBLs). Clear identification of risk factors for ESBL-producing infections is necessary. Therefore, efficient strategies can be developed to decrease outbreak of these infections. The aim of this study was to determine the antibacterial susceptibility and ESBLs patter...
متن کاملMolecular Epidemiology of ESBL Genes and Multi-Drug Resistance in Diarrheagenic Escherichia coli strains Isolated from Adults in Iran
Resistance to oxyimino cephalosporins antibiotics in Enterobacteriaceae is primarily done by the extended spectrum β-lactamases (ESBLs). Clear identification of risk factors for ESBL-producing infections is necessary. Therefore, efficient strategies can be developed to decrease outbreak of these infections. The aim of this study was to determine the antibacterial susceptibility and ESBLs patter...
متن کاملMolecular Epidemiology of ESBL Genes and Multi-Drug Resistance in Diarrheagenic Escherichia Coli Strains Isolated from Adults in Iran
Resistance to oxyimino cephalosporins antibiotics in Enterobacteriaceae is primarily done by the extended spectrum β-lactamases (ESBLs). Clear identification of risk factors for ESBLs-producing infections is necessary. Therefore, efficient strategies can be developed to decrease outbreak of these infections. The aim of this study was to determine the antibacterial susceptibility and ESBLs patte...
متن کاملEvaluation of CIVA agar for rapid detection of extended spectrum beta- lactamases (ESBL) among isolates of Enterobacteriaceae.
The emergence of plasmid mediated extended spectrum b-lactamases (ESBLs) in members of family Enterobacteriaceae has become a worldwide problem. Many clinical microbiology laboratories make no effort to detect ESBL production by Gram negative bacilli and have problem to detect ESBL mediated resistance. The choice of optimal laboratory method for detection and surveillance of ESBL producing orga...
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ورودعنوان ژورنال:
دوره 2012 شماره
صفحات -
تاریخ انتشار 2012